434 Correlation between stratum corneum anti-oxidant barrier function and permeability barrier function
نویسندگان
چکیده
منابع مشابه
Skin barrier function and stratum corneum hydration
Under normal circumstances, epidermis must be as impermeable as possible except for a small amount of water loss to hydrate the outer layers of the SC. Although all living cells require water to function, some “dead” cells also require water to be metabolically active. As it is the case of corneocytes, epidermis must retain sufficient water to (a) hydrate the outer layers of the SC to maintain ...
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The stratum corneum dehydrates after exogenous hydration due to skincare or bathing. In this study, sheets of stratum corneum were isolated from reconstructed human epidermis and the barrier function and structure of these sheets were assessed during drying with the aim of improving our understanding of skincare. Water diffusion through the sheets of stratum corneum decreased with drying, accom...
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Skin permeation for the occupational chemicals mainly depends on the Stratum Corneum (SC), which behaves as a barrier against the entrance of any substance applied on it. The hydration state of the SC plays a crucial role for its barrier function and the permeation process, especially for the water-soluble substances. In this work the relationship of the environmental Relative Humidity (RH) and...
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Tight junction (TJ) is recognized as a second barrier of the skin. Altered expression of TJ proteins in various skin diseases characterized by the abnormal permeability barrier such as psoriasis suggests that TJ could be affected by stratum corneum (SC) barrier status. However, the physiological relationship between SC and TJ barrier remains to be investigated. Therefore, we examined the effect...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2017
ISSN: 0022-202X
DOI: 10.1016/j.jid.2017.02.453